Llanos Silva Miguel

Director Unidad Académica Nutrición Humana
Profesor Asociado
Unidad Académica: 
Email: 
mllanos@inta.uchile.cl
Teléfono: 
(56) 229781483

Publicaciones

2017 Castaño E, Caviedes L, Hirsch S, Llanos M, Iñiguez G, Ronco AM. Folate transporters in placentas from preterm newborns and their relation to cord blood folate and vitamin B12 levels. PLoS One. 2017 Jan 19;12(1):e0170389
2016 Caviedes L, Iñiguez G, Hidalgo P, Castro JJ, Castaño E, Llanos M, Hirsch S, Ronco AM. Relationship between folate transporters expression in human placentas at term and birth weights. Placenta 2016; 38:24-28
2016 Rodriguez JM, Monsalves-Alvarez M, Henriquez S, Llanos MN, Troncoso R. Glucocorticoid resistance in chronic diseases. Steroids. 2016; 115:182-192
2015 Penailillo R, Guajardo A, Llanos M, Hirsch S, Ronco AM. Folic acid supplementation during pregnancy induces sex-specific changes in methylation and expression of placental 11β-hydroxysteroid dehydrogenase 2 in rats. PLoS One 2015; 10(3):e0121098
2015 Orellana-Serradell O, Poblete CE, Sanchez C, Castellón EA, Gallegos I, Huidobro C, Llanos MN, Contreras HR. Proapoptotic effect of endocannabinoids in prostate cancer cells. Oncol Rep 2015; 33(4):1599-1608
2015 Piñuñuri R, Mardones C, Valenzuela C, Estay P, Llanos M. Exposición prenatal a drogas de abuso y crecimiento de lactantes de CONIN Valparaíso, Chile(Exposition to drugs of abuse in pregnancy and breastfed babies growth in CONIN Valparaíso, Chile). Nutr Hosp 2015; 31(5):2070-2078
2015 Aguirre CA, Castillo VA, Llanos MN. The endocannabinoid anandamide during lactation increases body fat content and CB1 receptor levels in mice adipose tissue. Nutr Diabetes 2015 Jun 22; 5:e167
2014 Castro F, Harari F, Llanos M, Vahter M, Ronco AM. Maternal-child transfer of essential and toxic elements through breast milk in a mine-waste polluted area. Am J Perinatol 2014; 31(11):993-1002
2012 Zepeda R, Castillo P, Sáez D, Llanos MN, Ronco AM. Cardiac tissue injury resistance during myocardial infarction at adulthood by developmental exposure to cadmium. Cardiovasc Toxicol 2012; 12(1):64-72
2012 Aguirre CA, Castillo VA, Llanos MN. Excess of the endocannabinoid anandamide during lactation induces overweight, fat accumulation and insulin resistance in adult mice. Diabetol Metab Syndr 2012 Jul 23;4(1):35
2012 Castillo P, Ibáñez F, Guajardo A, Llanos MN, Ronco AM. Impact of cadmium exposure during pregnancy on hepatic glucocorticoid receptor methylation and expression in rat fetus. PLoS One 2012; 7(9):e44139
2012 Harari F, Ronco AM, Concha G, Llanos M, Grandér M, Castro F, Palm B, Nermell B, Vahter M. Early-life exposure to lithium and boron from drinking water. Reprod Toxicol 2012; 34(4):552-560
2011 Valenzuela CA, Castillo VA, Aguirre C, Ronco AM, Llanos MN. The CB1 receptor antagonist SR141716A reverses adult male mice overweight and metabolic alterations induced by early stress. Obesity (Silver Spring) 2011; 19(1):29-35
2011 Ronco AM, Montenegro M, Castillo P, Urrutia M, Saez D, Hirsch S, Zepeda R, Llanos MN. Maternal exposure to cadmium during gestation perturbs the vascular system of the adult rat offspring. Toxicol Appl Pharmacol 2011; 251(2):137-145
2010 Ronco AM, Llaguno E, Epuñan MJ, Llanos MN. Effect of cadmium on cortisol production and 11beta-hydroxysteroid dehydrogenase 2 expression by cultured human choriocarcinoma cells (JEG-3).Toxicol In Vitro 2010; 24(6):1532-1537
2010 Ronco AM, Gutierrez Y, Gras N, Muñoz L, Salazar G, Llanos MN. Lead and arsenic levels in women with different body mass composition. Biol Trace Elem Res 2010; 136(3):269-278
2009 Ronco AM, Urrutia M, Montenegro M, Llanos MN. Cadmium exposure during pregnancy reduces birth weight and increases maternal and foetal glucocorticoids. Toxicol Lett 2009; 188(3):186-191
2009 Llanos MN, Ronco AM. Fetal growth restriction is related to placental levels of cadmium, lead and arsenic but not with antioxidant activities. Reprod Toxicol 2009; 27(1):88-92
2008 Hirsch S, Ronco AM, Guerrero-Bosagna C, De la Maza MP, Leiva L, Barrera G, Llanos M, Alliende MA, Silva F, Bunout D. Methylation status in healthy subjects with normal and high serum folate concentration. Nutrition 2008; 24(11-12):1103-1109
2008 Hirsch S, Ronco AM, Pinardi G, Montequin MJ, Leiva L, De la Maza MP, Llanos M, Bunout D. Lack of effect of diet-induced hypomethylation on endothelium-dependent relaxation in rats. Clin Nutr 2008; 27(6):895-899
2007 Ronco AM, Llanos M, Tamayo D, Hirsch S. 5-Methyltetrahydrofolic acid stimulates endothelin-1 production in low density lipoprotein-treated human endothelial cells. Nutr Metab Cardiovasc Dis 2007; 17:188-194
2007 Ronco AM, Llanos M, Tamayo D, Hirsch S. Anandamide inhibits endothelin-1 production by human cultured endothelial cells: A new vascular action of this endocannabinoid. Pharmacology 2007; 79(1):12-16
2006 Ronco AM, Garrido F, Llanos MN. Smoking specifically induces metallothionein-2 isoform in human placenta at term. Toxicology 2006; 223(1-2):46-53
2005 Ronco AM, Arguello G, Suazo M, Llanos MN. Increased levels of metallothionein in placenta of smokers. Toxicology 2005; 208(1):133-139
2005 Ronco AM, Arguello G, Muñoz L, Gras N, Llanos M. Metals content in placentas from moderate cigarette consumers: correlation with newborn birth weight. Biometals 2005; 18(3):233-241
2005 Ronco AM, Garrido A, Llanos MN, Guerrero-Bosagna C, Tamayo D, Hirsch S. Effect of homocysteine, folates, and cobalamin on endothelial cell- and copper-induced LDL oxidation. Lipids 2005; 40(3):259-264
2003 Llanos M, Ronco AM, Aguirre MC. Specific strynchnine binding sites on acrosome-associated membranes of golden hamster spermatozoa. Biochem Biophys Res Commun 2003; 306(2):376-381
2002 Ronco AM, Moraga P, Llanos M. Arachidonic acid release from rat Leydig Cells. The involvement of G protein, phospholipase A2 and regulation of cAMP production. J Endocrinol 2002; 172 (1):95-104
2001 Contreras HR, Llanos M. Detection of progesterone receptors in human spermatozoa and their correlation with morphological and functional properties. Int J Androl 2001; 24:246-252
2001 Llanos M, Ronco AM, Aguirre MC, Meizel S. Hamster sperm glycine receptor: evidence for its presence and involvement in the acrosome reaction. Mol Reprod Dev 2001; 58:205-215
2001 Ronco AM, Valdes K, Marcus D, Llanos M. The mechanism for lindane-induced inhibition of steroidogenesis in cultured rat Leydig cells. Toxicology 2001; 159:99-106
2000 Ronco AM, Llanos M. Effect of human chorionic gonadotropin derivatives on Leydig cell function. Horm Res 2000; 54:157-163
1998 Llanos M. Thapsigargin stimulates acrosomal exocytosis in hamster spermatozoa. Mol Reprod Dev 1998; 51:84-91
1997 Moraga P, Llanos M, Ronco AM. Arachidonic acid release from rat Leydig cells depends on the presence of luteinizing hormone/human chorionic gonadotrophin receptors. J Endocrinol 1997; 154:201-209
1994 Llanos M. Evidence in support of a role for Ca2+-activated K+ channels in the hamster sperm acrosome reaction. J Exp Zool 1994; 269:484-488
1994 Morales P, Socias T, Cortez J, Llanos M. Evidences for the presence of a chymotrypsin-like activity in human spermatozoa with a role in the acrosome reaction. Mol Reprod Dev 1994; 38:222-230
1994 Llanos M, Ronco AM. Sperm phospholipid methyltransferase activity during preparation for exocytosis. Cell Biochem Funct 1994; 12:289-296
1993 Llanos M, Morales P, Riffo M. Studies of lysophospholipids related to the hamster sperm acrosome reaction in vitro. J Exp Zool 1993; 267:209-216
1993 Llanos M, Vigil P, Salgado AM, Morales P. Inhibition of the acrosome reaction by trypsin inhibitors and prevention of penetration of spermatozoa through the human zona pellucida. J Reprod Fertil 1993; 97:173-178
1993 Morales P, Llanos M, Yovich JL, Cummins JM, Vigil P. Pentoxifylline increases sperm penetration into zona-free hamster oocytes without increasing the acrosome reaction. Andrología 1993; 25:359-362
1993 Ronco AM, Llanos M, Valladares L. Human chorionic gonadotropin and free beta molecules stimulate phospholipid methylation in intact rat Leydig cells. Steroids 1993; 58:314-319
1992 Morales P, Llanos M, Gutierrez G, Kohen P, Vigil P, Vantman D. The acrosome reaction-inducing activity of individual human follicular fluid samples is highly variable and is related to the steroid content. Hum Reprod 1992; 7(5):646-651
1991 Llanos M, Riffo MS. Inhibitors of the high conductance Ca++ activated K+ channel inhibit the hamster sperm acrosome reaction in vitro. Mol Androl 1991; 3:271-289
1985 Llanos M, Ronco AM, Pino AM, Valladares L. The transmethylations inhibitor 3-deazaadenosine, inhibits in vitro testosterone production by rat testis interstitial cell stimulated with HCG. J Steroid Biochem 1985; 23:73-76
2014 Valenzuela C, Castillo V, Ronco AM, Aguirre C, Hirsch S, Llanos M. Sistema endocanabinoide y desarrollo de esteatosis hepática (A role for the endocannabinoid system in hepatic steatosis). Rev Méd Chil 2014; 142(3):353-360
2011 Pacheco R, Bay C, Gutiérrez Y, Salazar G, Muñoz L, Llanos M, Ronco AM. Contenido de plomo sanguíneo y composición corporal en mujeres jóvenes expuestas a humo de madera en la ciudad de Temuco (Blood lead levels and body composition in young women exposed to wood smoke in the city of Temuco). Rev Chil Nutr 2011; 38(4): 414-421
2010 Valenzuela C, Aguirre C, Castillo V, Ronco AM, Llanos M. Participación del sistema endocanabinoide en el desarrollo de obesidad (A role for the endocannabinoid system in obesity). Rev Med Chil 2010;138(5):621-629
2001 Ronco AM, Llanos M, Valladares L, Garrido A. Riesgo potencial para la salud humana de los xenobióticos ambientales como moduladores endocrinos (Potential health risks of environmental xenobiotics as endocrine modulators). Rev Chil Nutr 2001; 28(3):406-413
1999 Ronco AM, Llanos M, Valladares L. Anabólicos en producción pecuaria: un riesgo para la salud del consumidor? (Use of anabolics in livestock: a health risk for the consumer?). Rev Chil Nutr 1999; 26:288-294
1999 Ronco AM, Llanos M, Valladares L. Anabólicos en producción pecuaria: un riesgo para la salud del consumidor? (Use of anabolics in livestock: a health risk for the consumer?). Rev Chil Nutr 1999; 26:288-294
1989 Llanos M. La reacción acrosómica en espermatozoide de mamífero. Aspectos bioquímicos (The mammalian sperm acrosome reaction. A biochemical view). Arch Biol Med Exp 1989; 22(1):25-36
1991 Saavedra I, Valderas R, Letelier S, Boj T, Llanos M. Análisis de la ley de educación superior (Analysis of the high level educational law). Santiago: CPU; 1991
2005 Uauy R, Rojas C, Llanos A, Mena P. Dietary essential fatty acids in early postnatal life: Long-term outcomes. In: Hornstra G, Uauy R, Yang X., editors. The impact of maternal nutrition on the offspring. Basel: Nestec Ltd, Vevey and S. Karger; 2005. p.101-136 (Nestlé Nutrition Workshop Series. Pediatric Program; v.55)
1995 Morales P, Llanos M. Role of the acrosome reaction in egg vestments and plasma membrane penetration. In: Fénichel P, Parinaud J., editors. Human sperm acrosome reaction. Montrouge, France: John Libbey Eurotext Limited; 1995-1996. p.133-149 (Colloque INSERM; v.236)
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