Imbalance in metals homeostasis leads to several problems for the human health. From a systemic biology perspective, our research line has been focused in understanding how changes in bioavailability of metals alter the organism. Our laboratory is a pioneer in research of System Biology and Metals. We have published several articles in this field, developing new protocols in terms of transcriptional regulatory networks construction and metal metabolism analysis.
Grado Académico
- Doctor en Ciencias, mención Biología Molecular, Celular y Neurociencias
Unidad Académica
Nutrición Básica
Laboratorio
Áreas de interés
Adjuntos
| 2016 | Bordron P, Latorre M, Cortés MP, González M, Thiele S, Siegel A, Maass A, Eveillard D. Putative bacterial interactions from metagenomic knowledge with an integrative systems ecology approach. Microbiologyopen 2016; 5(1):106-117 |
| 2016 | Cordero N, Maza F, Navea-Perez H, Aravena A, Marquez-Fontt B, Navarrete P, Figueroa G, González M, Latorre M, Reyes-Jara A. Different tanscriptional responses from slow and fast growth rate strains of Listeria monocytogenes adapted to low temperature. Front Microbiol 2016 Mar 1; 7:229 |
| 2016 | Latorre M, Cortés MP, Travisany D, Di Genova A, Budinich M, Reyes-Jara A, Hödar C, González M, Parada P,Bobadilla-Fazzini RA, Cambiazo V, Maass A. The bioleaching potential of a bacterial consortium. Bioresour Technol 2016 Jul 6; 218:659-666 |
| 2016 | Del Pozo T, Gutiérrez-Garcia R, Latorre M, González M, Suazo M. Identification of reference genes for quantitative real-time PCR studies in human cell lines under copper and zinc exposure. Biometals. 2016; 29(5):935-944 |
| 2016 | DebRoy S, Saldaña M, Travisany D, Montano A, Galloway-Peña J, Horstmann N, Yao H, González M, Maass A,Latorre M, Shelburne SA. A multi-serotype approach clarifies the catabolite control protein a regulon in the major human pathogen group a streptococcus. Sci Rep. 2016 Sep 1; 6:32442 |
| 2016 | Acuña M, Castro-Fernández V, Latorre M, Castro J, Schuchman EH, Guixé V, González M, Zanlungo S. Structural and functional analysis of the ASM p.Ala359Asp mutant that causes acid sphingomyelinase deficiency. Biochem Biophys Res Commun. 2016 Oct 21;479(3):496-501 |
| 2015 | Quiroz N, Rivas N, Del Pozo T, Burkhead J, Suazo M, González M, Latorre M. Transcriptional activation of glutathione pathways and role of glucose homeostasis during copper imbalance. Biometals 2015; 28(2):321-328 |
| 2015 | Latorre M, Quesille-Villalobos AM, Maza F, Parra A, Reyes-Jara A. Synergistic effect of copper and low temperature over Listeria monocytogenes. Biometals 2015; 28(6):1087-1092 |
| 2015 | Mandakovic D, Cabrera P, Pulgar R, Maldonado J, Aravena P, Latorre M, Cambiazo V, González M. Complete genome sequence of Microbacterium sp. CGR1, bacterium tolerant to wide abiotic conditions isolated from the Atacama Desert. J Biotechnol 2015; 216:149-150 |
| 2015 | Latorre M, Low M, Gárate E, Reyes-Jara A, Murray BE, Cambiazo V, González M. Interplay between copper and zinc homeostasis through the transcriptional regulator Zur in Enterococcus faecalis. Metallomics 2015; 7(7):1137-1145 |
| 2014 | Latorre M, Galloway-Peña J, Roh JH, Budinich M, Reyes-Jara A, Murray BE, Maass A, González M. Enterococcus faecalis reconfigures its transcriptional regulatory network activation at different copper levels. Metallomics 2014; 6(3):572-581 |
| 2014 | Travisany D, Cortés MP, Latorre M, Di Genova A, Budinich M, Bobadilla-Fazzini RA, Parada P, González M, Maass A. A new genome of Acidithiobacillus thiooxidans provides insights into adaptation to a bioleaching environment. Res Microbiol 2014 2014; 165(9):743-752 |
| 2012 | Hödar C, Moreno P, di Genova A, Latorre M, Reyes-Jara A, Maass A, González M, Cambiazo V. Genome wide identification of Acidithiobacillus ferrooxidans (ATCC 23270) transcription factors and comparative analysis of ArsR and MerR metal regulators. Biometals 2012; 25(1):75-93 |
| 2012 | López G, Latorre M, Reyes-Jara A, Cambiazo V, González M. Transcriptomic response of Enterococcus faecalis to iron excess. Biometals 2012; 25(4):737-747 |
| 2011 | Latorre M, Olivares F, Reyes-Jara A, López G, González M. CutC is induced late during copper exposure and can modify intracellular copper content in Enterococcus faecalis. Biochem Biophys Res Commun 2011; 406(4):633-637 |
| 2010 | Reyes-Jara A, Latorre M, López G, Bourgogne A, Murray BE, Cambiazo V, González M. Genome-wide transcriptome analysis of the adaptive response of Enterococcus faecalis to copper exposure. Biometals 2010; 23(6):1105-1112 |